Life choices
When used in metaculture, life choices refers broadly to the important decisions that you have to make in your life to build sustainable happiness and fulfillment, and the relevant information about the universe that is needed to inform those decisions.
What is Relevant?
So much of spirituality and speculative scientific theories like quantum mechanics spend a lot of time focusing on aspects of the universe that are irrelevant to our life choices.
Does it matter if there is a multiverse? Or if we are living in a simulation? Or if the deist version of god set the universe in motion? In all cases we still exist within a single, procedurally generated universe that, according to every confirmed observation, conforms to consistent physical laws.
And we must figure out how to live a happy life, having found ourselves existing within such a universe. To do so it is important to separate the signal from the noise when informing those decisions.
What is Best?
Once we've determined what information is relevant to consider for our life choices, it becomes a matter of determining best practices based on the available information to find a course that is likely to lead to happiness.
In life we rarely deal with complete and incontrovertible information. Most of the time you have to take the best available information and place a bet on what you think is most likely. When viewed this way it becomes easy to discard more unlikely theories and move past indecision and agnosticism.